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cell surface

Wednesday 29 October 2003

Embryonic morphogenesis requires the execution of complex mechanisms that regulate the local behaviour of groups of cells. The orchestration of such mechanisms has been mainly deciphered through the identification of conserved families of signalling pathways that spatially and temporally control cell behaviour.

Adhesion and cortical actin networks are regulators of cell surface mechanics. A range of developmental phenomena can be explained by the regulation of cell surface tension.


- Lecuit T, Lenne PF. Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis. Nat Rev Mol Cell Biol. 2007 Aug;8(8):633-44. PMID: 17643125