Monday 19 May 2008
Monosomy 7 has been described in myelodysplastic syndromes and acute myeloid or lymphoblastic leukemias, as well as in several benign or malignant solid tumors. It is not usual in adipose tissue tumors.
myelodysplastic syndrome (MDS or myelodysplasia)
- Myelodysplastic syndrome (MDS) is a clonal hematopoietic disorder that often results in progression to acute myeloid leukemia (AML), particularly when additional genetic abnormalities are present, such as monosomy 7.
spindle cell liposarcoma without 12q amplification (#18617058#)
Italiano A, Chambonniere ML, Attias R, Chibon F, Coindre JM, Pedeutour F. Monosomy 7 and absence of 12q amplification in two cases of spindle cell liposarcomas. Cancer Genet Cytogenet. 2008 Jul 15;184(2):99-104. PMID: #18617058#
Parker TM, Klaassen RJ, Johnston DL. Spontaneous remission of myelodysplastic syndrome with monosomy 7 in a young boy. Cancer Genet Cytogenet. 2008 Apr 15;182(2):122-5. PMID: #18406874#