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Wednesday 23 April 2008

The soluble APP (sAPP) ectodomain is proposed to be involved in different physiological processes.

sAPP is predicted to regulate neuronal processes such as neurite outgrowth, synaptogenesis, synaptic plasticity and neuronal excitability and exerts neurotrophic and protective effects, indicating a potential role in learning and memory.

sAPP seems to play a role in neuronal stem cell division.

See also