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consumptive hypothyroidism

Friday 26 October 2007

Consumptive hypothyroidism is due to a vascular tumor expressing type 3 iodothyronine deiodinase.

The inactivation rate of thyroid hormone by D3 in tumors, as vascular tumors, can stress the secretory capacity even of the TSH-stimulated normal adult thyroid gland.


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- Huang SA, Fish SA, Dorfman DM, Salvatore D, Kozakewich HP, Mandel SJ, Larsen PR. A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. J Clin Endocrinol Metab. 2002 Oct;87(10):4457-61. PMID: 12364418