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metapneumovirus

Friday 26 October 2007

Human metapneumovirus (hMPV) is a recently discovered human virus that causes significant respiratory infections.

BAL

- epithelial degenerative changes
- eosinophilic cytoplasmic inclusions within epithelial cells
- multinucleate giant cells
- histiocytes

Lung biopsy

- chronic airway inflammation
- intraalveolar foamy
- hemosiderin-laden macrophages

References

- Vargas SO, Kozakewich HP, Perez-Atayde AR, McAdam AJ. Pathology of human metapneumovirus infection: insights into the pathogenesis of a newly identified respiratory virus. Pediatr Dev Pathol. 2004 Sep-Oct;7(5):478-86; PMID: 15547771