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organelles

Thursday 16 October 2003

Intracellular organelle transport is essential for morphogenesis and functioning of the cell.

Types

- endoplasmic reticulum
- Golgi apparatus
- Mitochondria
- peroxysomes
- lysosomes

Intercellular membrane transport

Cellular organelles in the exocytic and endocytic pathways have a distinctive spatial distribution. They communicate through an elaborate system of vesiculo-tubular transport (vesicular transport or vesicle transport).

Pathology

- organelle diseases

  • mitochondrial diseases
  • peroxisomal diseases
  • lysosomal diseases

- organelle lesions

  • mitochondrial lesions
  • peroxisomal lesions
  • lysosomal lesions

See also

- cellular organelle movement
- organelle protein import
- organelle transport
- organelle proteomics
- target organelle

Videos

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References

- Böck G, Steinlein P, Huber LA. Cell biologists sort things out: Analysis and purification of intracellular organelles by flow cytometry. Trends Cell Biol. 1997 Dec;7(12):499-503. PMID: 17709014

- Voeltz GK, Prinz WA. Sheets, ribbons and tubules - how organelles get their shape. Nat Rev Mol Cell Biol. 2007 Mar;8(3):258-64. PMID: 17287811

- Brunet S, Thibault P, Gagnon E, Kearney P, Bergeron JJ, Desjardins M. Organelle proteomics: looking at less to see more. Trends Cell Biol. 2003 Dec;13(12):629-38. PMID: 14624841

- Kunau WH, Agne B, Girzalsky W. The diversity of organelle protein import mechanisms. Trends Cell Biol. 2001 Sep;11(9):358-61. PMID: 11529240