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penile myointimoma

Friday 28 September 2007

Penile myointimoma is a rare benign myointimal proliferation occurring exclusively within the corpus spongiosum of the glans penis and is most commonly described in adult patients.

Synopsis

- myointimal proliferation of the preexisting vascular spaces of the corpus spongiosum, creating a multinodular/plexiform architecture.

Immunohistochemistry

- strong cytoplasmic immunoreactivity for smooth muscle actin in the lesional cells
- collarette of native smooth muscle highlighted by desmin

References

- McKenney JK, Collins MH, Carretero AP, Boyd TK, Redman JF, Parham DM. Penile Myointimoma in Children and Adolescents: A Clinicopathologic Study of 5 Cases Supporting a Distinct Entity. Am J Surg Pathol. 2007 Oct;31(10):1622-1626. PMID: #17895766#