Wednesday 26 September 2007
transmural epithelioid cell granulomas (EPGs)
- predominantly nonsuppurative
- surrounded by a lymphoid cuff composed of small lymphocytes.
- EPGs with suppuration of the centers of the granulomas (central microabscesses)
EPGs composed of numerous histiocytes with or without epithelioid cell features, along with scattered small T-lymphocytes and plasmacytoid monocytes.
- None of the EPGs contain monocytoid B-cells.
EPGs usually surrounded by surface IgM/D+ small mantle zone lymphocytes.
CNA.42 immunostaining occasionally demonstrated residual follicular dendritic cells in the center of the EPGs.
Yersinia enterocolitica appendicitis (#17189675#)
cat scratch disease (numerous monocytoid B-cells)
lymphogranuloma venerum (numerous monocytoid B-cells)
Kojima M, Morita Y, Shimizu K, Yoshida T, Yamada I, Togo T, Johshita T. Immunohistological findings of suppurative granulomas of Yersinia enterocolitica appendicitis: a report of two cases. Pathol Res Pract. 2007;203(2):115-9. PMID: #17189675#