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t(9;11;19)(p22;q23;p13.3)

Tuesday 18 September 2007

Pathology

- ANLL

Molecular biology

- fusion gene between MLL (ALL1) at 11q23 and MLLT3 (AF9) at 9p22

Variants

- t(9;11)(p22;q23)

References

- Vieira L, Sousa AC, Matos P, Marques B, Alaiz H, Ribeiro MJ, Braga P, da Silva MG, Jordan P. Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3). Genes Chromosomes Cancer. 2006 May;45(5):455-69. PMID: 16450356