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cellular mesoblastic nephroma

Wednesday 29 August 2007

Etiology

- translocation t(12-15)(p13;q25) creating ETV6-NTRK3 gene fusion

See also

- pediatric renal tumors

  • mesoblastic nephroma

- congenital fibrosarcoma

Open access references

- ETV6 rearrangements in patients with infantile fibrosarcomas and congenital mesoblastic nephromas by fluorescence in situ hybridization. Adem C, Gisselsson D, Dal Cin P, Nascimento AG. Mod Pathol. 2001 Dec;14(12):1246-51. PMID: #11743047# [Free]

- Detection of the ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors. Argani P, Fritsch M, Kadkol SS, Schuster A, Beckwith JB, Perlman EJ. Mod Pathol. 2000 Jan;13(1):29-36. PMID: #10658907# [Free]

- ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma. Knezevich SR, Garnett MJ, Pysher TJ, Beckwith JB, Grundy PE, Sorensen PH. Cancer Res. 1998 Nov 15;58(22):5046-8. PMID: #9823307# [Free]

- Congenital mesoblastic nephroma t(12;15) is associated with ETV6-NTRK3 gene fusion: cytogenetic and molecular relationship to congenital (infantile) fibrosarcoma. Rubin BP, Chen CJ, Morgan TW, Xiao S, Grier HE, Kozakewich HP, Perez-Atayde AR, Fletcher JA. Am J Pathol. 1998 Nov;153(5):1451-8. PMID: #9811336# [Free]