Home > G. Tumoral pathology > Cancer molecular profiling > Cancer cytogenetics > Tumoral translocations > t(2;11)(q37;q23)

t(2;11)(q37;q23)

Monday 23 July 2007

Translocation t(2;11)(q37;q23) is a rare recurrent cytogenetic abnormality associated with de novo and therapy-related acute myeloid leukemia. It results in a MLL-SEPT2 fusion gene.

Molecular biology

- MLL/SEPT2 fusion gene

References

- van Binsbergen E, de Weerdt O, Buijs A. A new subtype of MLL-SEPT2 fusion transcript in therapy-related acute myeloid leukemia with t(2;11)(q37;q23): a case report and literature review. Cancer Genet Cytogenet. 2007 Jul 1;176(1):72-5. PMID: #17574968#