Home > A. Molecular pathology > ORMDL3

ORMDL3

Saturday 21 July 2007

ORMDL3, a member of a gene family that encodes transmembrane proteins anchored in the endoplasmic reticulum.

Pathology

- Genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma. (17611496)

See also

- ORMDLs: ORMDL1, ORMDL2, ORMDL3

References

- Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.
Nature. 2007 Jul 4; PMID: 17611496

- Katoh M, Katoh M. Identification and characterization of human ZPBP-like gene in silico. Int J Mol Med. 2003 Sep;12(3):399-404. PMID: 12883658

- Hjelmqvist L, Tuson M, Marfany G, Herrero E, Balcells S, Gonzalez-Duarte R. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol. 2002;3(6):RESEARCH0027. PMID: 12093374