Friday 13 July 2007
The chromatoid body is a unique cloud-like structure of male germ cells. It moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades.
microRNA and RNA-decay pathways converge to the chromatoid body.
This highly specialized structure might function as an intracellular focal domain that organizes and controls RNA processing in male germ cells.
Kotaja N, Sassone-Corsi P. The chromatoid body: a germ-cell-specific RNA-processing centre. Nat Rev Mol Cell Biol. 2007 Jan;8(1):85-90. PMID: #17183363#