- Human pathology

Home > B. Cellular pathology > chromatoid body

chromatoid body

Friday 13 July 2007

The chromatoid body is a unique cloud-like structure of male germ cells. It moves dynamically in the cytoplasm of haploid spermatids, but its function has remained elusive for decades.

microRNA and RNA-decay pathways converge to the chromatoid body.

This highly specialized structure might function as an intracellular focal domain that organizes and controls RNA processing in male germ cells.


- Kotaja N, Sassone-Corsi P. The chromatoid body: a germ-cell-specific RNA-processing centre. Nat Rev Mol Cell Biol. 2007 Jan;8(1):85-90. PMID: 17183363