bone metastasis

The most common malignant bone marrow tumor is metastatic carcinoma.

In adults, metastases from the prostate, breast, kidney, and lung account for the majority of cases.

The axial skeleton and proximal femur are the most common sites, whereas the distal elbow and knee are uncommon sites.

Histologically and cytologically, malignant epithelial tissue fragments are identified in a background of bone marrow elements, with or without inflammation and necrosis.

Immunohistochemical staining can help to further identify the tissue of origin.

Digital slides

 UI:754 - Bone marrow: metastatic adenocarcinoma

Videos

 Metastasis of an adenocarcinoma in the bone marrow (by Washington Deceit)

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See also

 Adenocarcinomas
 Metastasis