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fetal urethral obstruction

Tuesday 22 May 2007

Etiology (Examples)

- urethral agenesis
- urethral atresia
- posterior urethral valves (PUV)

Complications

- urethral obstruction sequence (UOS)

  • megacystis
    • prune belly sequence
  • bilateral megaureteres
  • bilateral hydronephrosis
  • bilateral ostructive renal dysplasia
  • oligohydramnios sequence

Case records

- Case record #10038

References

- Berry C. Patterns of congenital lower urinary tract obstructive uropathy.
Pediatr Dev Pathol. 2003 Mar-Apr;6(2):202-3; author reply 203. PMID: 12574913

- Volmar KE, Fritsch MK, Perlman EJ, Hutchins GM. Patterns of congenital lower urinary tract obstructive uropathy: relation to abnormal prostate and bladder development and the prune belly syndrome. Pediatr Dev Pathol. 2001 Sep-Oct;4(5):467-72. PMID: 11779049

- Poucell-Hatton S, Huang M, Bannykh S, Benirschke K, Masliah E. Fetal obstructive uropathy: patterns of renal pathology. Pediatr Dev Pathol. 2000 May-Jun;3(3):223-31. PMID: 10742409

- Fryns JP, Vandenberghe K, Deschrijver D. Early urethral obstruction sequence and unbalanced translocation with terminal 10p duplication/1p deficiency. Genet Couns. 1997;8(4):349-50. PMID: 9457507

- van Buggenhout G, Cooreman G, Thienpont L, Fryns JP. Early urethral obstruction sequence and trisomy of the long arm of chromosome 1. Ann Genet. 1995;38(2):106-7. PMID: 7486825

- Bierkens AF, Feitz WF, Nijhuis JG, de Wildt MJ, Flos MS, de Vries JD. Early urethral obstruction sequence: a lethal entity? Fetal Diagn Ther. 1996 Mar-Apr;11(2):137-45. PMID: 8838771