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Thursday 17 May 2007

RDC1, chemokine CXC motif receptor 7


- HMGA2/CXCR7 fusion gene in lipomas

  • CXCR7 at 2q37
  • HMGA2 at 12q14

- CXCL12-CXCR7 axis contributes to the invasive phenotype of pancreatic cancer.

See also

- CXCRs (chemokine CXC motif receptors)


- Broberg K, Zhang M, Strombeck B, Isaksson M, Nilsson M, Mertens F, Mandahl N, Panagopoulos I. Fusion of RDC1 with HMGA2 in lipomas as the result of chromosome aberrations involving 2q35-37 and 12q13-15. Int J Oncol. 2002 Aug;21(2):321-6. PMID: 12118328