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lithium-associated parathyroid tumors

Monday 7 May 2007

See also

- parathyroid tumors
- lithium-associated hyperparathyroidism (HPT)
- comparative genomic hybridization (CGH)
- loss of heterozygosity (LOH)
- multiple endocrine neoplasia type 1 (MEN1)

CGH

- losses

  • 1p
  • 11
  • 15q
  • 22q

- gains

  • X chromosome

LOH

- 11q13 LOH

Somatic gene mutations

- somatic MEN1 mutation

Cancer loci

- MEN1 loci
- 1p34.3-pter
- 1q21-q32

References

- Dwight T, Kytola S, Teh BT, Theodosopoulos G, Richardson AL, Philips J, Twigg S, Delbridge L, Marsh DJ, Nelson AE, Larsson C, Robinson BG. Genetic analysis of lithium-associated parathyroid tumors. Eur J Endocrinol. 2002 May;146(5):619-27. PMID: #11980616#