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personalized medicine

Sunday 22 April 2007

The utility and limitations of personal genomic data can be discussed in three domains:
- pharmacogenomics,
- assessment of genetic predispositions for common diseases,
- identification of rare disease-causing genetic variants.

Open references

- Personalized medicine: hope or hype? Salari K, Watkins H, Ashley EA. Eur Heart J. 2012 Jul;33(13):1564-70. doi : heartj/ehs112" target="_blank">10.1093/eurheartj/ehs112 PMID: 22659199 [Free]


- G-DOC: A Systems Medicine Platform for Personalized Oncology. Madhavan S, Gusev Y, Harris M, Tanenbaum DM, Gauba R, Bhuvaneshwar K, Shinohara A, Rosso K, Carabet LA, Song L, Riggins RB, Dakshanamurthy S, Wang Y, Byers SW, Clarke R, Weiner LM. Neoplasia. 2011 Sep;13(9):771-83. PMID: 21969811 [Free]

- Jain KK. Challenges of drug discovery for personalized medicine. Curr Opin Mol Ther. 2006 Dec;8(6):487-92. PMID: 17243483