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2q37 LOH

Friday 20 April 2007

Tumors

- Wilms tumor (5%)
- oral squamous cell carcinoma (OSCC) (2q37.3)

Candidate genes

- LRP1B, CASP8, CASP10, BARD1, ILKAP, PPP1R7, and ING5

References

- Cengiz B, Gunduz M, Nagatsuka H, Beder L, Gunduz E, Tamamura R, Mahmut N, Fukushima K, Ali MA, Naomoto Y, Shimizu K, Nagai N. Fine deletion mapping of chromosome 2q21-37 shows three preferentially deleted regions in oral cancer. Oral Oncol. 2007 Mar;43(3):241-7. Epub 2006 Jul 20. PMID: #16857411#

- Beder LB, Gunduz M, Ouchida M, Fukushima K, Gunduz E, Ito S, Sakai A, Nagai N, Nishizaki K, Shimizu K. Genome-wide analyses on loss of heterozygosity in head and neck squamous cell carcinomas. Lab Invest. 2003 Jan;83(1):99-105. PMID: #12533690#