Home > D. Systemic pathology > Genetic and developmental anomalies > Chromosomal diseases > Ring chromosomes > ring chromosome 15

ring chromosome 15

Monday 26 March 2007

Synopsis

- growth retardation (100%)

- atrophic intestinal mucosa (3962666)
- variable mental retardation (95%)
- microcephaly (88%)
- hypertelorism (46%),
- triangular facies (42%) (3278612)
- delayed bone age (75%)
- brachydactyly (44%)
- speech delay (39%)
- frontal bossing (36%)
- anomalous ears (30%)
- cafe-au-lait spots (30%)
- cryptorchidism (30%)
- microcephaly (6468449)
- dysmorphism of ears, fingers and feet (6468449)
- primary gonadal hypoplasia (7116681)
- infertility (7105474)
- stillborn

- Malformations

- intrauterine growth retardation (17380471)
- Increased fetal nuchal fold (11746160)
- 15q26.1-qter deletion (17380471)

See also

- terminal 15q deletions

References

- Butler MG, Fogo AB, Fuchs DA, Collins FS, Dev VG, Phillips JA 3rd. Two patients with ring chromosome 15 syndrome. Am J Med Genet. 1988 Jan;29(1):149-54. PMID: 3278612