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CD3Z-associated primary T-cell immunodeficiency

Friday 16 March 2007

Etiology

- germline or somatic mutations in CD3Z-associated primary T-cell immunodeficiency (MIM.610163)

See also

- TCRs (T-cell antigen receptor complex)
- TCR subunits
- CD subunits

References

- Rieux-Laucat F, Hivroz C, Lim A, Mateo V, Pellier I, Selz F, Fischer A, Le Deist F. Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency. N Engl J Med. 2006 May 4;354(18):1913-21. PMID: #16672702#

- Le Deist F, de Saint Basile G, Rieux-Laucat F, Hivroz C, Fischer A. [CD3 complex and immunodeficiencies.] Med Sci (Paris). 2007 Feb;23(2):161-166. In french. PMID: #17291425#