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clear cell meningioma

Sunday 28 January 2007

Definition: Clear cell meningioma (CCM) is a rare variant of meningioma. It is rare tumor of the nervous system that usually occur in young patients and display high recurrence rates and potentially aggressive behavior. Although it has bland cytologic features, it has a higher rate of recurrence than does conventional meningioma.

Images

- Clear cell meningioma, WHO grade II.

Localization

- spinal/intradural (lumbar and thoracic)
- cerebellopontine angle
- supratentorial
- orbit (18193452)

Differential diagnosis

- microcystic meningioma
- hemangioblastoma
- clear cell ependymoma

Cytogenetics

- monosomy 22

See also

- clear cell tumors

References

- Benchetritt M, Hofman V, Long E, Odin G, Basc E, Pasquier B, Pedeutour F, Hofman P. Primary clear cell meningioma of the orbit mimicking a metastatic carcinoma: usefulness of immunohistochemistry and cytogenetic analysis.Virchows Arch. 2008 Feb;452(2):209-13. PMID: 18193452

- Oviedo A, Pang D, Zovickian J, Smith M. Clear cell meningioma: case report and review of the literature. Pediatr Dev Pathol. 2005 May-Jun;8(3):386-90. PMID: 16010490