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pseudo-Gaucher cell

Friday 29 December 2006

Pseudo-Gaucher cells are histiocytes with cytoplasm containing needle-like inclusions, resembling Gaucher’s cells.

Etiology (exemples)

- chronic myeloid leukaemia (CML)
- thalassaemia (4328400)
- multiple myeloma (380339)
- acute lymphoblastic leukaemia
- Hodgkin lymphoma (3103422)
- non-Hodgkin lymphoma
- myelodysplasia and myelodysplastic syndromes (10711256)

- mycobacterioses(16189163)

See also

- foamy macrophages (foamy histiocytes)

  • splenic foamy macrophages

References

- Dunn P, Kuo MC, Sun CF. Pseudo-Gaucher cells in mycobacterial infection: a report of two cases. J Clin Pathol. 2005 Oct;58(10):1113-4. PMID: 16189163

- Solis OG, Belmonte AH, Ramaswamy G, et al. Pseudogaucher cells in Mycobacterium avium intracellulare infection in acquired immune deficiency syndrome (AIDS). Am J Clin Pathol 1986;85:233–5. PMID: 3946307

- Links TP, Karrenbeld A, Steensma JT, et al. Fatal respiratory failure caused by pulmonary infiltration by pseudo-Gaucher cells. Chest 1992;101:265–6. PMID: 1729081

- Beutler E. Gaucheri’s disease. N Engl J Med 1991;325:1354–60.

- Zidar BL, Hartsock RJ, Lee RE, et al. Pseudo-Gaucher cells in the bone marrow of a patient with Hodgkin’s disease. Am J Clin Pathol 1987;87:533–6.

- Zaino EC, Rossi MB, Pham TD, et al. Gaucher’s cells in thalassemia. Blood 1971;38:457–62.

- Scullin DC, Shelburne JD, Cohen HJ. Pseudo-Gaucher cells in multiple myeloma. Am J Med 1979;67:347–52.

- Carrington PA, Stevens RF, Lendon M. Pseudo-Gaucher cells. J Clin Pathol 1992;45:360.

- Stewart AJ, Jones RD. Pseudo-Gaucher cells in myelodysplasia. J Clin Pathol 1999;52:917–18.