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Home > A. Molecular pathology > IL23R


MIM.607562 1p32.1-p31.2

Tuesday 26 December 2006

IL23 is a heterodimeric cytokine consisting of p19 (IL23A) (MIM.605580) and p40 (IL12B) (MIM.161561) subunits.

The p40 subunit also interacts with p35 (IL12A) (MIM.161560) to form IL12.

IL23, like IL12, binds to IL12RB1 (MIM.601604), but only IL12 binds to IL12RB2 (MIM.601642).

IL23R does not interact with IL12, but pairs with IL12RB1 to confer IL23 responsiveness on cells expressing both subunits.


- IL23R variants in

See also

- IBDs susceptibility


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