Saturday 18 November 2006
Plants have unique features that evolved in response to their environments and ecosystems.
A full account of the complex cellular networks that underlie plant-specific functions is still missing. It has been described a proteome-wide binary protein-protein interaction map for the interactome network of the plant Arabidopsis thaliana containing about 6200 highly reliable interactions between about 2700 proteins.
A global organization of plant biological processes emerges from community analyses of the resulting network, together with large numbers of novel hypothetical functional links between proteins and pathways.
It has been observed a dynamic rewiring of interactions following gene duplication events, providing evidence for a model of evolution acting upon interactome networks.
Alonso JM, Ecker JR. Moving forward in reverse: genetic technologies to enable genome-wide phenomic screens in Arabidopsis. Nat Rev Genet. 2006 Jul;7(7):524-36. PMID: 16755288