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prostatic partial atrophy

Partial atrophy is the most common benign mimicker of prostate cancer on needle biopsy. Recognition of the classic morphology of partial atrophy on routine hematoxylin and eosin-stained sections is critical to avoid misdiagnosing partial atrophy as adenocarcinoma.

PA foci do not represent a spectrum of proliferative inflammatory atrophy, justifying its term. (18162771)

References

- Wang W, Sun X, Epstein JI. Partial atrophy on prostate needle biopsy cores: a morphologic and immunohistochemical study. Am J Surg Pathol. 2008 Jun;32(6):851-7. PMID: 18408595

- Przybycin CG, Kunju LP, Wu AJ, Shah RB. Partial atrophy in prostate needle biopsies: a detailed analysis of its morphology, immunophenotype, and cellular kinetics. Am J Surg Pathol. 2008 Jan;32(1):58-64. PMID: 18162771