Human pathology

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penile squamous cell carcinoma

Penile squamous cell carcinoma is considered a disease of local-regional dissemination.

Widespread metastases occur in less than one third of patients. Local recurrence after limited surgical excision or partial penectomy is not uncommon, and it is noted in slow-growing verruciform tumors, intermediate grade superficially spreading lesions, and in poorly differentiated neoplasms.

References

- Velazquez EF, Soskin A, Bock A, Codas R, Barreto JE, Cubilla AL. Positive resection margins in partial penectomies: sites of involvement and proposal of local routes of spread of penile squamous cell carcinoma. Am J Surg Pathol. 2004 Mar;28(3):384-9. PMID: 15104302