Human pathology

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ovarian carcinomas

Epithelial ovarian carcinoma

Epithelial ovarian carcinoma is the leading cause of death from gynecologic cancer and one of the most frequent causes of fatal malignancy in women. The poor prognosis is likely related to the degree of peritoneal dissemination associated with ascites accumulation.

Approximately 25,000 ovarian cancers are diagnosed in the U.S. annually. 75% of cases diagnosed in the advanced stage when they are largely incurable.

LOH

- 8p12-p23

Amplifications

- 20q amplification

See also

- ovarian tumors