Human pathology

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nasal chondromesenchymal hamartoma

nasal chondroid hamartoma, NCMH

Nasal chondromesenchymal hamartoma (NCMH) is an extremely rare benign pediatric tumor that was described in 1998. Only 19 cases are reported in the literature in 2007.

Synospsi

- nasal obstruction
- recurrent sinusitis
- partially calcified soft-tissue mass obstructing the nasal cavity

Associations

- rare ovarian tumor
- pleuropulmonary blastoma (PPB)

References

- Johnson C, Nagaraj U, Esguerra J, Wasdahl D, Wurzbach D. Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor. Pediatr Radiol. 2007 Jan;37(1):101-4. PMID: 17091268

- Ozolek JA, Carrau R, Barnes EL, Hunt JL. Nasal chondromesenchymal hamartoma in older children and adults: series and immunohistochemical analysis. Arch Pathol Lab Med. 2005 Nov;129(11):1444-50. PMID: 16253025

- Norman ES, Bergman S, Trupiano JK. Nasal chondromesenchymal hamartoma: report of a case and review of the literature. Pediatr Dev Pathol. 2004 Sep-Oct;7(5):517-20. PMID: 15547776

- Hsueh C, Hsueh S, Gonzalez-Crussi F, Lee T, Su J. Nasal chondromesenchymal hamartoma in children: report of 2 cases with review of the literature. Arch Pathol Lab Med. 2001 Mar;125(3):400-3. PMID: 11231491

- Kim DW, Low W, Billman G, Wickersham J, Kearns D. Chondroid hamartoma presenting as a neonatal nasal mass. Int J Pediatr Otorhinolaryngol. 1999 Mar 15;47(3):253-9. PMID: 10321780