inflammatory bowel diseases
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Suceptibility
Locus IBD1
Locus IBD2
Locus IBD3
Locus IBD4
Locus IBD5 - 5q31 cytokine gene cluster
Locus IBD6
Locus CARD15
MDR1 Ala893 polymorphism (7q) (14610718)
variation in DLG5 gene (10q23) encoding a scaffolding protein involved in the maintenance of epithelial integrity (15107852)
Videos
Colonoscopy of ulcerative colitis
References
Ivanov AI, Nusrat A, Parkos CA. The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption. Novartis Found Symp. 2004;263:115-24; discussion 124-32, 211-8. PMID: 15669638
Mathew CG, Lewis CM. Genetics of inflammatory bowel disease: progress and prospects. Hum Mol Genet. 2004 Apr 1;13 Spec No 1:R161-8. PMID: 14764625
Podolsky DK. Inflammatory bowel disease. N Engl J Med. 2002 Aug 8;347(6):417-29. PMID: 12167685