hepatic tuberculoid granuloma
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hepatic epithelioid granuloma
Etiology
74% generalized granulomatous disease
4% primary hepatic disease
20-25% no etiology found
List
I. Infectious diseases (infections)
bacterial infections
- actinomycosis borrelia (Lyme disease)
- botryomycosis
- brucellosis
- cat-scratch disease
- granuloma inguinale
- listeriosis
- melioidosis
- nocardiosis
- proprioniosis
- staphylococcal infections
- primary syphilis, scondary syphilis
- tularemia
- typhoid
- Whipple disease
- yersiniosis (Yersinia enterolitica)
- mycobacterial infections
- tuberculosis
- atypical mycobacteria (Mycobacterium avium intracellulare)
- BCG infection
- leprosy
- chlamydial infections
- lymphopathia venereum
- psittacosis
fungal infections
- aspergillosis
- blastomycosis (North american and South american)
- candidiasis
- coccidioidomycosis
- paracoccidioidomycosis
viral infections
- virus C hepatitis (HVC) (8406419)
- histoplasmosis (Histoplasma capsulatum)
II. drug reaction
III. dysimmunity (immunological diseases)
immune deficiencies
IV. foreign materials
V. tumors (neoplasms)
VI. miscellaneous
biliary tract obstruction (bile granulomas)
chronic inflammatory bowel diseases
eosinophilic enteritis
jejuno-ileal bypass surgery
porphyria cutanea tarda
sarcoidosis
According to the localization of granulomas
ductal granulomas with ductal damage
- primary biliary cirrhosis
- drug injury
- sarcoidosis
periductal bile granulomas
- large-duct obstruction