granulosa-theca cell tumors
granulosa-stromal cell tumors
Granulosa cells are capable of releasing estrogen. The hormone may produce precocious puberty in children and cause endometrial hyperplasia in women. Granulosa cell tumors are slow growing tumors. 5-25% of these tumors exhibit malignant behavior. On the other hand, the pure thecomas are benign.
Types
adult-type granulosa-cell tumor
juvenile-type granulosa cell tumor
fibroma-thecoma tumor groups
Synopsis
most commonly oberved tumors in post-menopausal women
usually unilateral.
solid tumor with a white-yellow cut surface
Microscopically
- association of granulosa cells (granulosa cell tumor), theca cells (thecoma) or various proportions of both cells.
- tumor cells may be luteinized.
- The granulosa cells are cuboidal to polygonal cells that are arranged in cords, sheets or strands.
- The theca cells are spindle cells and are arranged in sheets.
See also
testicular tumors
ovarian tumors