giant cell transformation
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neonatal syncytial giant cell hepatitis, giant cell hepatitis, giant cell transformation of hepatocytes, hepatocytic giant cell transformation
Etiology:
viral hepatitis
- cytomegalovirus hepatitis (CMV hepatitis)
- rubella virus hepatitis
- herpes simplex virus hepatitis (HSV hepatitis)
- HPV
- HHV-6 hepatitis
- varicella hepatitis
- coxsackievirus hepatitis
- echovirus hepatitis
- reovirus 3 hepatitis
- parvovirus B19 hepatitis
- HIV hepatitis
- enterovirus hepatitis
- paramyxovirus hepatitis
- hepatitis A
- hepatitis B
- hepatitis C (rare)
bacterial hepatitis
- generalized bacterial sepsis
- syphilis (syphilitic hepatitis)
- listeriosis hepatitis
- tuberculosis (tuberculous hepatitis)
parasitic hepatitis (protozoan hepatitis)
- toxoplasmosis hepatitis
- extra-hepatic biliary atresia
- choledochal cyst
- intrahepatic bile duct paucity (biliary ductopenia) and Alagille disease
- hepatic cystic fibrosis
- familial intrahepatic cholestatic syndromes (FIHC)
- bile acid synthetic diseases (inborn errors of bile acid synthesis)
chromosomal anomalies
metabolic diseases
- alpha-1-antitrypsin deficiency
- galactosemia
- Niemann-Pick diseases
- Gaucher diseases
- mucolipidoses
- cerebrohepatorenal syndrome (Zellweger syndrome)
- acute tyrosinemia
- some mitochondriopathies
- some peroxysomopathies
autoimmune diseases (immunohemolytic diseases)
autoimmune hemolytic anemia (GCHAIHA)
- autoimmune hepatitis type II (LKM1+) (1)
- neonatal erythematosus lupus - systemic lupus (1,2,3)
cardiovascuar diseases
- endocardial cushion defect
- anomalous pulmonary venous return
neonatal hemochromatosis (fetal massive hepatic necrosis)
Associations
neonatal hemochromatosis (idiopathic iron storage syndrome)
Arnold-Chiari malformation
See also