fibrous histiocytoma
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Dermatofibroma, Sclerosing hemangioma, Histiocytoma cutis, Nodular subepidermal fibrosis
Type of fibrohistiocytic tumors.
Variants
cellular fibrous histiocytoma
aneurysmal fibrous histiocytoma
atypical fibrous histiocytoma (pseudosarcomatous fibrous histiocytoma)
epithelioid dermatofibroma (epithelioid fibrous histiocytoma)
Immunochemistry
strong tenascin positivity at the dermal-epidermal junction overlying the lesion (100%)
tenascin within the DF lesion (80%)
CD34+ (25%) DF
Factor XIIIa+ (95%) DF
Differential diagnosis
Dermatofibroma (fibrous histiocytoma) vs DFSP (11172295)
| DF | DFSP | |
| CD34 | 25% | 80% |
| FXIIIa | 95% | 15% |
| Tenascin in the tumor | 80% | 80% |
| Tenascin at the dermal-epidermal junction | 100% | 0% |
See also
- angiomatoid fibrous histiocytoma (specific tumoral entity)