extra-abdominal deep soft tissue leiomyoma
Synopsis
absence of nuclear atypia
absence of necrosis
no/minimal mitotic activity
Localization
deep somatic soft tissue of the lower extremity
upper extremity
trunk
axilla
back
affect sexes equally (7 male, 6 female)
circumscribed mass of mature smooth muscle cells
frequently calcified
mean mitotic activity of <1 mitosis/50 high power fields (HPF) (range 1-4 mitoses/50 HPF)
Immunochemistry
estrogen receptor negative
progesterone receptor negative
See also
intra-abdominal deep soft tissue leiomyoma
References
Billings SD, Folpe AL, Weiss SW. Do leiomyomas of deep soft tissue exist? An analysis of highly differentiated smooth muscle tumors of deep soft tissue supporting two distinct subtypes. Am J Surg Pathol. 2001 Sep;25(9):1134-42. PMID: 11688572