esophageal adenocarcinoma
Oesophageal and gastro-oesophgeal junction (GOJ) adenocarcinoma is increasing in incidence and has a poor outcome.
Comparative genomic hybridization (16479570)
losses
gains
Early adenocarcinoma of the esophagus (T1 stage)
Early (T1 stage) adenocarcinoma of the esophagus or gastroesophageal junction is a potentially curable disease.
See also
esophageal carcinomas
References
van Dekken H, Wink JC, Vissers KJ, van Marion R, Koppert LB, Tilanus HW, Siersema PD, Tanke HJ, Szuhai K, Hop WC. Genomic analysis of early adenocarcinoma of the esophagus or gastroesophageal junction: tumor progression is associated with alteration of 1q and 8p sequences. Genes Chromosomes Cancer. 2006 May;45(5):516-25. PMID: 16479570
Lin L, Wang Z, Prescott MS, van Dekken H, Thomas DG, Giordano TJ, Chang AC, Orringer MB, Gruber SB, Moran JV, Glover TW, Beer DG. Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma. Genes Chromosomes Cancer. 2006 Apr;45(4):319-31. PMID: 16320248