Human pathology

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botryoid rhabdomyosarcoma

botryoid embryonal rhabdomyosarcoma, embryonal botryoid embryonal rhabdomyosarcoma

Definition: Botryoid rhabdomyosarcoma is a subset of embryonal rhabdomyosarcoma. It accounts for 6% of all cases of rhabdomyosarcomas.

Botryoid rhabdomyosarcoma arises under the mucosal surfaces of body orifices; therefore, it is most commonly observed in areas such as the vagina, bladder, and nares.

Botryoid rhabdomyosarcoma is distinguished by the formation of polypoid and grapelike tumor masses. On histologic study, botryoid rhabdomyosarcoma demonstrates malignant cells in an abundant myxoid stroma.

Differential diagnosis

- botryoid tumors

See also

- rhabdomyosarcomas

References

- Riedlinger WF, Kozakewich HP, Vargas SO. Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. Pediatr Dev Pathol. 2005 Jul-Aug;8(4):427-34. PMID: 16220232