ductular reaction
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neoductular proliferation, portal ductal proliferation, ductular proliferation
Definition: Increase in the number and prominence of small biliary channels in and around the portal tracts.
Synopsis:
tubular to elongated profiles
lined by cuboidal or columnar epithelium
well-defined lumen or not
Etiology:
acute or chronic cholestasis
sepsis
massive hepatic necrosis
hepatic fibrosis
hepatic cirrhosis
miscellaneous
- nephronophthisis-associated hepatic disease
- hepatic Ellis-van Creveld disease
Elementary lesions associated:
bile plugs
ductular dilatation
neutrophilic infiltration
Differential diagnosis:
must be distinguished from interlobular bile ducts