Human pathology

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deletion 12(q15-q21.2)

interstitial deletion 12(q15-q21.2)

Interstitial deletions of the long arm of chromosome 12 are rare rearrangements with only 15 cases reported in the literature (2008).

Synopsis

- facial dysmorphism
- developmental delay
- ectodermal abnormalities
- cardiac malformations
- renal malformations

references

- Schluth C, Gesny R, Borck G, Redon R, Abadie V, Kleinfinger P, Munnich A, Lyonnet S, Colleaux L. New case of interstitial deletion 12(q15-q21.2) in a girl with facial dysmorphism and mental retardation. Am J Med Genet A. 2008 Jan 1;146(1):93-6.PMID: 18076123