classic Hodgkin lymphoma
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cHL, classic Hodgkin’s disease, classical Hodgkin lymphoma
Subtypes
nodular sclerosing Hodgkin lymphoma
mixed cellularity Hodgkin lymphoma
lymphocyte rich classical Hodgkin lymphoma
lymphocytic depleted Hodgkin lymphoma (lymphocyte depletion)
- diffuse fibrose variant
- reticular variant
Microscopical synopsis
heterogenous population
Sternberg cells
Hodgkin cells
Variants
interfollicular Hodgkin lymphoma (6859389)
Associations
mantle cell lymphoma (14576485, 14657719)
Differential diagnosis
nodular lymphocyte predominant Hodgkin lymphoma
reactive lymphadenitis (3366442)
Cytgenetics
t(l4;18)
t(2;5)
del(lp)
dup(lq)
del(6q)
del(7q)
Chr.4 rearrangments
- 4q25-28 rearrangements
See also
References
Hammerschmidt W, Sugden B. Epstein-Barr virus sustains Burkitt’s lymphomas and Hodgkin’s disease. Trends Mol Med. 2004 Jul;10(7):331-6. PMID: 15242681