CAVs
Caveolin is a major structural protein of caveolae, also known as plasmalemmal vesicles.
Members
caveolin-1 (CAV1)
caveolin-2 (CAV2)
caveolin-3 (CAV3) (mutations in some muscular dystrophies)
Expression (Examples)
type I pneumocytes
capillary endothelial cells
Pathology
mutations of caveolin-3 in some muscular dystrophies
References
Williams TM, Lisanti MP. The caveolin proteins.
Genome Biol. 2004;5(3):214. PMID: 15003112
Galbiati F, Razani B, Lisanti MP. Caveolae and caveolin-3 in muscular dystrophy. Trends Mol Med. 2001 Oct;7(10):435-41. PMID: 11597517
Couet J, Belanger MM, Roussel E, Drolet MC. Cell biology of caveolae and caveolin. Adv Drug Deliv Rev. 2001 Jul 28;49(3):223-35. PMID: 11551396
Gumbleton M, Abulrob AG, Campbell L. Caveolae: an alternative membrane transport compartment. Pharm Res. 2000 Sep;17(9):1035-48. PMID: 11087034