Human pathology

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acute myeloid leukemia M4

Subtypes

- acute myeloid leukemia M4eo (M4eo-ANLL) (M4-ANLL with marked eosinophilia) (all M4eo share 16q22 anomaly)

Cytogenetics

- t(X;11)(q24;q23) (MLL-SEPT6 fusion gene)
- t(11;19)(q23;p13) (7679464)
- inv(16)(p13q22) (20%)