Human pathology

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Mesothelial cysts

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Hepatic mesothelial cysts Hepatic mesothelial cysts Hepatic mesothelial cysts Splenic mesothelial cyst Splenic mesothelial cyst (open) Splenic mesothelial cyst (open) Splenic multilocular mesothelial cysts Splenic multilocular mesothelial cysts
mesothelial inclusion cysts, benign cystic mesothelioma

Types

- unifocal
- multifocal

Localization

Localization

- diaphragmatic mesothelial cysts
- peritoneal surface (surface of the peritoneum)

  • peritoneal cul-de-sac
  • intestines
  • urinary bladder
  • uterine adnexa
  • round ligament within the pelvis
  • inguinal canal
  • free-floating cysts in the peritoneal cavity

- visceral

Synopsis

- Gross appearance: polycystic lesions
- Size: microscopic size to 2 cm in diameter
- thin-walled, semitranslucent, filled with clear or yellowish fluid or gelatinous contents
- cysts were with a single layer of flattened or cuboid mesothelial cells (CK+, calretinin+)
- diffuse squamous cell metaplasia
- cells focally forming small papillae
- vacuolated cells
- no mucus

Immunohistochemistry

- CK +
- calretin +

Associations

- diaphragmatic defect (diaphragmatic hernia)

References

- Arber DA, Strickler JG, Weiss LM. Splenic mesothelial cysts mimicking lymphagiomas. Am J Surg Pathol. 1997 Mar;21(3):334-8. PMID: 9060604