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ARHGAPs

Definition: Protein family of Rho GTPase-activating protein. GTPase-activating proteins (ARHGAPs), such as ARHGAP23, inactivate RHO family proteins (RHOs) by stimulating their hydrolysis of GTP.

The RHO family of small GTPases (RHOs), as RHOA (MIM.165390), are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form.

Members

ARHGAP1 ARHGAP2 ARHGAP3ARHGAP4ARHGAP5ARHGAP6ARHGAP7ARHGAP8ARHGAP9ARHGAP10
ARHGAP11ARHGAP12ARHGAP13ARHGAP14ARHGAP15ARHGAP16ARHGAP17ARHGAP18ARHGAP19ARHGAP20
ARHGAP21ARHGAP22ARHGAP23ARHGAP24ARHGAP25ARHGAP26ARHGAP27ARHGAP28ARHGAP29

Pathology

Keywords