AKT2
AKT2 (MIM.164731) is the isoform of AKT 1 and is enriched in insulin-responsive tissues and has been implicated in the metabolic actions of the hormone.
Pathology
mutations and/or amplification in tumors
- ovarian carcinomas (16839745, 16721043)
- pancreatic carcinomas (14735903)
- mammary carcinomas (12032855)
- embryonal rhabdomyosarcoma (16790082)
See also