Loss of 4q21.23-22.1 is a prognostic marker for disease free and overall survival in non-small cell lung cancer. (#25501003#)
Loss of 4q21.23-22.1 is a prognostic marker for disease free and overall survival in non-small cell lung cancer. Uzunoglu FG, Dethlefsen E, Hanssen A, Wrage M, Deutsch L, Harms-Effenberger K, Vashist YK, Reeh M, Sauter G, Simon R, Bockhorn M, Pantel K, Izbicki JR, Wikman H. PLoS One. 2014 Dec 11;9(12):e113315. (...)
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Metastasis, not the primary tumor, is responsible for the majority of breast cancer-related deaths. Emerging evidence indicates that breast cancer stem cells (CSCs) and the epithelial-to-mesenchymal transition (EMT) cooperate to produce circulating tumor cells (CTCs) that are highly competent for metastasis.
CTCs with both CSC and EMT characteristics have recently been identified in the bloodstream of patients with metastatic disease.
Breast CSCs have elevated tumorigenicity required for (...)
A new 3-tier pattern-based system to classify endocervical adenocarcinoma was recently presented.
Pattern A tumors were characterized by well-demarcated glands frequently forming clusters or groups with relative lobular architecture.
Pattern B tumors demonstrated localized destructive invasion defined as desmoplastic stroma surrounding glands with irregular and/or ill-defined borders or incomplete glands and associated tumor cells (individual or small clusters) (...)
SDHA-associated renal cell carcinoma
Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is an emerging provisional entity included in the 2013 International Society of Urological Pathology Vancouver Classification.
Most genomic alterations in patients with SDH-deficient RCCs involve the SDHB subunit, and the associated renal tumors have loss of immunohistochemical SDHB expression and distinctive morphologic features.
Renal tumors less commonly possess genomic alterations (...)
renal simple cysts
renal atypical cysts
Components or structures are entities assembling to form another biological components.
gastric nodular lymphoid hyperplasia
duodenal nodular lymphoid hyperplasia
intestinal nodular lymphoid hyperplasia
colonic nodular lymphoid hyperplasia
nodular lymphoid hyperplasia
diffuse nodular lymphoid hyperplasia of the colon
immunodeficiency syndromes Nodular lymphoid hyperplasia (NLH) of the gastrointestinal tract is a rare disorder associated with immunodeficiency syndromes. common variable immunodeficiency (CVID) CIVD is the second most prevalent primary immunodeficiency disorder after selective immunoglobulin A deficiency.
lymphoid nodule (lymphatic nodule)
digestive nodular lymphoid (...)
digestive lymphoid nodule gastric lymphoid nodule intestinal lymphoid nodule colonic lymphoid nodule
lymphoid nodule in the bladder
lymphoid nodule in the gall bladder
bone marrow lymphoid nodule