mucus producing cell
respiratory mucus producing cells
digestive mucus producing cells
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mucus producing cell
Definition: Foveolar cells are mucus producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid.
Foveolar cells are also known as "surface mucous cells" or "mucous neck cells", depending on the location. These cells line the gastric mucosa and gastric pits.
The mucous secreting cells of the stomach can be distinguished histologically from the intestinal goblet cells.
Definition: Goblet cells are glandular simple columnar epithelial cells whose function is to secrete mucin, which dissolves in water to form mucus. They use both apocrine and merocrine methods for secretion.
The term goblet refers to these cells’ goblet-like shape. The apical portion is shaped like a cup, as it is distended by abundant mucinogen granules; its basal portion is shaped like a stem, as it is narrow for lack of these granules.
There are other cells that (...)
Definition: Intestinal metaplasia is the transformation (metaplasia) of epithelium, usually of the stomach or the esophagus , to a type that bears some resemblance to the intestine as seen in Barrett’s esophagus.
Chronic infection caused by H. pylori infection in the stomach and GERD in the esophagus are seen as the primary instigators of metaplasia and subsequent adenocarcinoma formation.
Initially, the transformed eptithelium bears resemblance to the small intestine; in the later (...)
Single cell genomics of the brain: focus on neuronal diversity and neuropsychiatric diseases. Iourov IY, Vorsanova SG, Yurov YB. Curr Genomics. 2012 Sep;13(6):477-88. doi: 10.2174/138920212802510439 . PMID: #23449087# [Free]
Genome-wide copy number profiling of single cells in S-phase reveals DNA-replication domains. Van der Aa N, Cheng J, Mateiu L, Esteki MZ, Kumar P, Dimitriadou E, Vanneste E, Moreau Y, Vermeesch JR, Voet T. Nucleic (...)
In the postgenome era, biology and medicine are rapidly evolving towards quantitative and systems studies of complex biological systems.
Emerging breakthroughs in microfluidic technologies and innovative applications are transforming systems biology by offering new capabilities to address the challenges in many areas, such as single-cell genomics, gene regulation networks, and pathology.
quantitative biomolecular analysis
systems biomolecular analysis (...)
gastric endocrine cells
Endocrine cells of the gastric oxyntic mucosa, and especially the enterochromaffin-like (ECL) cells, are the progenitors of gastrin-promoted proliferative lesions whose tumorigenic potential largely depends on the background condition in which they arise.
gastric endocrine cell hyperplasia
gastric carcinoid tumor
Multinucleate epithelial change in colorectal hyperplastic polyps
Hyperplastic polyps containing multinucleated epithelial giant cells (MEGs) show active inflammation and apoptosis, and in most there was also focal inflammation and apoptosis in the adjacent mucosa.
Inflammation in conjunction with the increased epithelial proliferation characteristics of hyperplastic polyps could be the mechanism for the MEG formation.
Multinucleate epithelial change in colorectal (...)
Cytomegalovirus infection as isolated inflammatory polyps of the gastrointestinal tract.
Gastrointestinal involvement by cytomegalovirus (CMV) infection is a well recognised complication in patients taking steroid/immunosuppressive therapy or suffering from immunodeficiency and debilitating diseases. Rarely, CMV may affect immunocompetent healthy individuals. However, CMV infection presenting as isolated inflammatory polyps is unusual.
Cytomegalovirus infection presenting as (...)