Humpath.com - Human pathology

Most recent articles

• vacuolization of syncytiotrophoblast

  22 August

  Images
  Suspected skeletal dysplasia with pulmonary hypoplasia @ 37gw. Small placenta (304g) : GM1 gangliosidosis https://twitter.com/sranna86/status/899780925445165056 Placental metabolic dysfunction due to GM1 gangliosidosis Placental shows vacuolisation of syncytiotrophoblast, intermediate trophoblast, and stromal Hofbauer cells. AR lysosomal storage disease characterised by def of acid beta-galactosidase resulting in accumulation of gangliosides and MPS in (...)

• breast reduction mammaplasty

  22 August

  Breast reduction mammaplasty (RMP)
  Breast reduction mammaplasty (RMP) for symptomatic macromastia or correction of asymmetry is performed in more than 100 000 patients per year in the United States.
  The reported incidence of significant pathologic findings (SPF), that is, carcinoma and atypical hyperplasia, ranges from 0.06% to 12.8%. No standard pathology assessment for RMP exists.
  Open references
  Recommendations for Pathologic Evaluation of Reduction Mammoplasty Specimens. 2017. (...)

• cervical cystic anomalies

  21 August

  These lesions vary in prevalence from common (thyroglossal duct cyst , branchial cleft cyst , and cystic hygroma ) to very rare (thymic cyst and cervical bronchogenic cyst ). The absolute number remains unknown.
  See also : cervical cysts
  Location
  central cervical cysts
  lateral cervical cysts
  Types
  congenital cystic masses of the neck :
  cervical thyroglossal duct cyst
  cervical branchial cleft cyst
  cervical cystic hygroma
  cervical dermoid cyst and cervical epidermoid cyst (...)

• cystic cervical lymph node metastasis

  21 August

  See also
  cystic lymph node metastasis
  cervical cystic anomalies / cervical cysts
  Examples
  cystic lymph node metastasis of papillary thyroid carcinoma
  cystic lymph node metastasis of squamous cell carcinoma

• tubal epithelial dysplasia

  21 August, by admin

  serous tubal intraepithelial carcinoma STIC
  See also : serous tubal intraepithelial carcinoma STIC
  Examples
  Tubal epithelial dysplasia https://twitter.com/huda_rr1/status/899233810201534465
  See also
  tubal epithelial anomalies

• tubal epithelial anomalies

  21 August

  Examples
  tubal epithelial dysplasia https://twitter.com/huda_rr1/status/899233810201534465

• stress granules

  21 August

  Stress Granule
  Cytoplasmic stress granules (SGs) are critical for facilitating stress responses and for preventing the accumulation of misfolded proteins.
  Oxidative stress is one of the conditions that induce SG formation. SGs regulate redox levels, and SG formation in turn is differently regulated by various types of oxidative stress.
  Pathology
  SGs have been linked to the pathogenesis of neurodegenerative diseases, in part because SGs share many components with neuronal granules. (...)

• cervical cytology

  20 August

  See also : PAP test / PAP smear

• ADAR2

  20 August

  Pathology
  Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis. ADAR2 is overexpressed in EC and that the increase in expression positively correlates with the aggressiveness of the tumor. Furthermore, silencing of ADAR2 in three EC cell lines resulted in a decreased proliferation rate, increased apoptosis, and reduced migration capabilities in vitro. ADAR2 functions as an oncogene in endometrial carcinogenesis and could be a (...)

• Toker cells

  20 August

  Dr. Cyril Toker (1930-2015).
  Definition: Toker cells are epithelial cells with clear cytoplasm localized within the nipple epidermis.
  See also
  mammary anomalies mammary epithelial anomalies

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