Humpath.com - Human pathology

Most recent articles

• MEIS1-NCOA2

  6 September

  Pathology
  Novel MEIS1-NCOA2 gene fusions define a distinct primitive spindle cell sarcoma of the kidney. (#30179902#)

• prostatic urethral polyp

  30 August

  Definition : polyp of prostatic tissue protruding in the urethral lumen.
  Synopsis
  Mostly in adult men
  Usually asymptomatic but may cause hematuria
  Cystoscopically, the lesions appear as discrete small papillary growths that may be solitary or extensive, producing a velvety coating on the mucosa
  Microscopy
  Papillary fronds contain a thin fibrovascular core and are covered by normal prostatic acinar epithelium
  Occasionally, foci of residual urothelium can be seen
  See also (...)

• urethral anomalies

  30 August

  Types
  caruncle
  diverticula
  inverted papilloma
  leiomyoma
  nephrogenic adenoma / mesonephric adenoma
  papilloma
  polypoid urethritis
  prolapse
  prostatic urethral polyp
  See also
  urethra

• glandular atypia

  30 August

  Atypical Glands
  Examples
  Atypical Glands in Prostate Biopsy http://webpathology.com/image.asp?case=22&n=1
  See also
  atypia

• atypia

  30 August

  Examples
  cellular atypia
  epithelial atypia glandular atypia

• focal glandular atypia

  30 August

  Examples
  atypical small acinar proliferation (ASAP)

• perivascular cell tumors

  29 August

  Types
  glomus tumor / glomic tumor
  hemangiopericytoma / solitary fibrous tumor
  perivascular epithelioid cell tumor (PEComa / PEComas )
  See also
  tumors vascular tumors

• prostatic atypical adenomatous hyperplasia

  29 August

  prostatic adenosis PO
  Definition: A microscopic proliferation of small glands with minimal atypia; may be mistaken for low grade adenocarcinoma. It is sound almost exclusively in transition zone (2% of TURPs, < 1% of core biopsies).
  Microscopy
  The glands are variable in size and show round, oval, or irregular lumina. The cytoplasm is pale in contrast to the amphophilic cytoplasm usually seen in cancer.
  The nuclei are not enlarged appreciably and prominent nucleoli are not (...)

• PIN-like carcinoma

  29 August

  Definition: Prostatic intraepithelial neoplasia like (PIN-like ductal) carcinoma are rare tumors characterized by crowded, often cystically dilated glands architecturally resembling high-grade prostatic intraepithelial neoplasia, lined by malignant pseudostratified columnar epithelium.
  The largest prior series studied 9 radical prostatectomies (RPs) and suggested a behavior similar to Gleason score 6.
  Paywall references
  PIN-like (Ductal) Adenocarcinoma of the Prostate. Paulk A, (...)

• pancreatic mucoepidermoid carcinoma

  29 August

  "Mucoepidermoid carcinoma (MEC)" has been accepted as a synonym for pancreatic adenosquamous carcinoma (ASC). Pancreatic ASC can show salivary gland-type MEC-like morphology.
  Pan-MEC is histologically and biologically high-grade and unrelated to CRTC1/3-MAML2 fusion gene, unlike Sal-MEC which is related to CRTC1/3-MAML2 fusion gene. Pan-MEC is not a pancreatic counterpart of CRTC1/3-MAML2 fusion gene-related Sal-MEC. (#30138216#)
  Paywall references
  "Pancreatic Mucoepidermoid Carcinoma" (...)

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